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SPRO is now undervalued and could go up 355%

Jul 11, 2025, 12:00 PM
-7.03%
What does SPRO do
Spero Therapeutics, based in Cambridge, Massachusetts, develops treatments for multi-drug resistant infections and rare diseases, with key products including SPR720, tebipenem HBr, and SPR206. The company went public on November 2, 2017, and employs 46 people.
Based on our analysis, Spero Therapeutics has been rated 4 out of 5 stars for being undervalued. Several key financial ratios indicate that the company may present an attractive investment opportunity compared to its sector peers. Firstly, Spero's Price-to-Book (PB) Ratio stands at 1.22, significantly lower than the sector average of 2.71. A lower PB ratio often suggests that a stock is undervalued relative to its assets, indicating potential for future price appreciation. In terms of profitability, Spero's Net Profit Margin is reported at -142.91, compared to the sector's -137.57. Although both figures are negative, Spero's margin indicates a more significant loss, warranting scrutiny. This could be a result of high research and development expenses typical in the biotech industry, which may not necessarily reflect long-term inefficacy. The Return on Equity (ROE) for Spero is -148.66, compared to the sector’s -76.41. This indicates that Spero is currently experiencing a higher loss on equity, which may deter some investors. However, it could also suggest that once the company stabilizes or achieves profitability, there could be substantial upside. Lastly, the Return on Assets (ROA) ratio for Spero is -62.03, against a sector average of -47.59. This lower ROA indicates less efficient asset utilization, but again, it reflects the high costs associated with drug development. Overall, while Spero Therapeutics shows negative financial metrics relative to its sector, its PB ratio suggests that it is undervalued, offering potential for future growth. This is not a comprehensive overview of our valuation, and should not be viewed as financial advice. Always do your own research before considering an investment.
📡️ Health Care

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