enCore Energy and Lusochimica: Pioneering Sustainable Practices in Pharmaceutical Production
- enCore Energy is not mentioned in the content provided; the focus is exclusively on Lusochimica's SmartNEBI project.
- The SmartNEBI project emphasizes sustainable nebivolol production using biocatalysis and flow chemistry techniques.
- Lusochimica's recognition with the STEP Seal highlights its commitment to sustainable practices in the pharmaceutical industry.

Lusochimica's SmartNEBI Project: Pioneering Sustainable Pharmaceutical Production
Lusochimica S.p.A., part of the Menarini Group, achieves a significant milestone by receiving the STEP Seal from the European Commission on September 22, 2025. This accolade highlights the company’s commitment to sustainable practices in the pharmaceutical industry, particularly through its innovative SmartNEBI project. The initiative focuses on the sustainable synthesis of nebivolol, a vital active pharmaceutical ingredient (API) used in cardiovascular treatments. By integrating cutting-edge technologies, the SmartNEBI project not only aims to enhance the efficiency of nebivolol production but also to reduce the overall environmental impact associated with pharmaceutical manufacturing.
The SmartNEBI project stands out for its incorporation of biocatalysis and flow chemistry techniques. These methods allow for more selective and efficient chemical transformations, which are essential for producing high-quality APIs while minimizing waste. The project aligns with the Strategic Technologies for Europe Platform's objectives, emphasizing the importance of technological innovation and industrial advancement across Europe. The recognition from the European Commission underscores Lusochimica’s role in addressing pressing health challenges through innovative solutions that prioritize sustainability. By focusing on cleaner production methods, the SmartNEBI initiative contributes to a more resilient and environmentally conscious pharmaceutical sector.
Roberto Falorni, General Manager of Lusochimica, expresses pride in this recognition, which reflects the Menarini Group's ongoing dedication to research and innovation. He asserts that the SmartNEBI project represents a pivotal advancement toward greener pharmaceutical practices, particularly in optimizing energy use and reducing solvent consumption. This project not only demonstrates Lusochimica's leadership in sustainable development but also sets a benchmark for the industry as a whole, showcasing the potential for pharmaceutical companies to contribute positively to environmental goals while advancing healthcare solutions.
In addition to the STEP Seal, the SmartNEBI project benefits from funding under the EU4Health program, which addresses cross-border health issues through innovative projects. This support highlights the European Commission's commitment to fostering advancements in health and sustainability. The successful implementation of SmartNEBI could serve as a model for future pharmaceutical projects, encouraging similar initiatives that prioritize environmental responsibility alongside healthcare efficacy.
The recognition of Lusochimica's efforts through the STEP Seal not only elevates the company's profile within the pharmaceutical industry but also emphasizes the growing importance of sustainable practices in drug production. As the industry faces increasing scrutiny regarding its environmental impact, initiatives like SmartNEBI could reshape the future of pharmaceutical manufacturing, paving the way for a more sustainable and health-conscious global landscape.