Sanofi Transfers Caprelsa® Rights to ESTEVE for Global Cancer Treatment Expansion
- Sanofi grants ESTEVE rights to Caprelsa® (vandetanib) for over 50 countries, enhancing ESTEVE's cancer treatment portfolio.
- Caprelsa® is vital for treating medullary thyroid carcinoma, offering significant survival benefits for affected patients.
- The acquisition strengthens both companies' positions in specialized therapies, focusing on rare diseases and improving patient outcomes.

Sanofi and ESTEVE Forge Strategic Alliance for Caprelsa® Rights
In a significant move within the pharmaceutical industry, ESTEVE announces its agreement with Sanofi to acquire the rights to Caprelsa® (vandetanib) in more than 50 countries. This acquisition marks a pivotal expansion of ESTEVE’s portfolio, particularly in the realm of specialized treatments aimed at addressing rare and aggressive forms of cancer. Caprelsa® is indicated for the treatment of medullary thyroid carcinoma, a rare and often aggressive cancer that arises from the parafollicular cells of the thyroid gland. This cancer type is characterized by elevated levels of calcitonin, making effective treatment crucial for patient survival and quality of life.
Vandetanib, the active ingredient in Caprelsa®, operates as a protein tyrosine kinase inhibitor. Its mechanism of action includes slowing tumor growth by reducing blood supply to cancer cells, thus providing an essential therapeutic option for both adults and pediatric patients aged five and older diagnosed with this challenging condition. José María Giménez-Arnau, ESTEVE’s Chief Scientific & Medical Officer, highlights the critical nature of this acquisition, which supports patients who often rely on surgical intervention as their primary treatment. However, the addition of medications like vandetanib can significantly enhance management strategies for this patient population, allowing for better control of tumor progression.
The acquisition aligns with ESTEVE’s strategic focus on expanding its capabilities in rare diseases, particularly following its recent ventures into endocrinology and onco-endocrinology. The company has already enhanced its treatment offerings with new therapies addressing conditions like endogenous Cushing's syndrome and Adrenocortical Carcinoma. Jacob Tolstrup, ESTEVE’s Chief Commercial Officer, emphasizes the company’s commitment to addressing unmet medical needs globally. By integrating Caprelsa® into its portfolio, ESTEVE aims to reinforce its position as a leader in specialized therapies, thus improving patient outcomes in oncology and beyond. The completion of the Caprelsa® transaction awaits customary regulatory approvals, which are anticipated to finalize soon.
The collaboration between ESTEVE and Sanofi represents a strategic alignment of resources and expertise, allowing both companies to leverage their strengths in the pharmaceutical landscape. As ESTEVE continues to build its portfolio in specialized treatments, it positions itself to make a significant impact on patient care, particularly in the field of rare and complex diseases. The acquisition of Caprelsa® not only enhances ESTEVE's offerings but also illustrates the ongoing evolution and partnerships within the pharmaceutical sector aimed at delivering innovative solutions for patients in need.