Back/Bio-Techne Innovates Spatial Biology with RNAscope™ and COMET™ Technologies for Enhanced Diagnostics
tech·September 26, 2025·tech

Bio-Techne Innovates Spatial Biology with RNAscope™ and COMET™ Technologies for Enhanced Diagnostics

ED
Editorial
Cashu Markets·2 min read
TL;DR
  • Bio-Techne enhances spatial biology with RNAscope™ and Lunaphore COMET™ technologies for simultaneous RNA and protein detection.
  • RNAscope™ aids in identifying vital biomarkers, improving diagnoses of lymphoid malignancies and patient outcomes.
  • Bio-Techne showcases innovations at the NSH Convention, emphasizing the transformative impact on pathology and clinical diagnostics.

Bio-Techne Advances Spatial Biology with Cutting-Edge Technology

Bio-Techne Corporation, a frontrunner in providing life science tools, announces significant enhancements to its spatial biology offerings, particularly through its RNAscope™ ISH technology and Lunaphore COMET™ systems. These innovative tools facilitate the simultaneous detection of RNA and protein biomarkers on the same tissue section, marking a pivotal development in bridging translational research with clinical applications. This integration enhances pathological workflows, allowing clinicians and researchers to extract more comprehensive insights from tissue samples, which can be crucial for accurate diagnoses and effective treatment plans.

The RNAscope™ technology empowers researchers to identify clinically relevant biomarkers, such as viral markers and chromosomal translocations. This capability is especially vital in the context of diagnosing lymphoid malignancies, where accurate biomarker detection can significantly influence patient outcomes. Complementing this, the COMET™ system provides high-throughput analysis, streamlining spatial multiomic workflows and enabling researchers to process multiple biomarkers concurrently. Recent studies underscore the practical applications of these technologies, particularly in evaluating B-cell clonality through IGLL5 detection, which is critical for assessing the presence and nature of certain malignancies.

Bio-Techne’s commitment to innovation is further exemplified by its upcoming participation in the National Society of Histotechnology (NSH) Convention, taking place from September 26 to 30 in Long Beach, California. At the convention, the company will present various case studies and research findings that showcase the transformative potential of RNAscope™ and COMET™ technologies. Dr. Ryan Bremer will discuss the advantages of RNAscope™ over traditional diagnostic methods, while Dr. Ishani Das will present her research on utilizing RNAscope™ for B-cell clonality assessment. Additionally, Dr. Antonio Sorrentino will shed light on how COMET™ technology can enhance the diagnostic process for lymphoid malignancies, reinforcing Bio-Techne's role in advancing pathology through technology.

In summary, Bio-Techne is poised to revolutionize the field of pathology with its spatial biology innovations. By enabling a deeper understanding of tissue samples through simultaneous biomarker detection, the company not only enhances research capabilities but also contributes to improved clinical diagnostics. These advancements are expected to play a critical role in the future of healthcare, where precision medicine increasingly relies on detailed molecular insights. Bio-Techne's ongoing dedication to integrating advanced technologies into routine pathology practice reflects its commitment to enhancing diagnostic accuracy and ultimately improving patient care.