SIBONE

Mika Nishimura sold 4,100 shares of SIBN on 12 March. They now own 32,716 SIBN shares, or a 11% holding decrease.

Anthony J Recupero sold 21,049 shares of SIBN on 17 February. They now own 243,418 SIBN shares, or a 8% holding decrease.

Laura Francis sold 93,475 shares of SIBN on 17 February. They now own 544,369 SIBN shares, or a 15% holding decrease.

Michael A Pisetsky sold 20,756 shares of SIBN on 17 February. They now own 285,974 SIBN shares, or a 7% holding decrease.

Anshul Maheshwari sold 21,528 shares of SIBN on 17 February. They now own 266,466 SIBN shares, or a 7% holding decrease.

Jeffrey W Dunn sold 20,000 shares of SIBN on 8 January. They now own 80,115 SIBN shares, or a 20% holding decrease.

Laura Francis sold 3,968 shares of SIBN on 26 April. They now own 70,524 SIBN shares, or a 5% holding decrease.

ORBIMED ADVISORS LLC bought 200,000 shares of SIBN on 19 October. They now own 985,368 SIBN shares, or a 25% holding increase.

Skyline Venture Partners V LP bought 325,000 shares of SIBN on 19 October. They now own 4,419,985 SIBN shares, or a 8% holding increase.

David P Bonita bought 200,000 shares of SIBN on 19 October. They now own 985,368 SIBN shares, or a 25% holding increase.

Timothy Petersen bought 200,000 shares of SIBN on 19 October. They now own 1,695,036 SIBN shares, or a 13% holding increase.

John Gordon Freund bought 301,096 shares of SIBN on 19 October. They now own 4,419,985 SIBN shares, or a 7% holding increase.

Anthony J Recupero sold 1,427 shares of SIBN on 15 April. They now own 19,273 SIBN shares, or a 7% holding decrease.

Scott A Yerby sold 10,349 shares of SIBN on 15 April. They now own 9,984 SIBN shares, or a 51% holding decrease.

Scott A Yerby sold 10,133 shares of SIBN on 15 May. They now own 185,187 SIBN shares, or a 5% holding decrease.

Michael A Pisetsky sold 2,000 shares of SIBN on 16 May. They now own 18,073 SIBN shares, or a 10% holding decrease.

Laura Francis sold 6,486 shares of SIBN on 28 May. They now own 70,524 SIBN shares, or a 8% holding decrease.

Scott A Yerby sold 648 shares of SIBN on 6 June. They now own 8,960 SIBN shares, or a 7% holding decrease.

Scott A Yerby sold 30,000 shares of SIBN on 28 June. They now own 144,030 SIBN shares, or a 17% holding decrease.

W Carlton Reckling sold 15,000 shares of SIBN on 28 June. They now own 10,049 SIBN shares, or a 60% holding decrease.

Anthony J Recupero sold 1,500 shares of SIBN on 1 July. They now own 19,273 SIBN shares, or a 7% holding decrease.

Scott A Yerby sold 10,133 shares of SIBN on 15 July. They now own 132,873 SIBN shares, or a 7% holding decrease.

W Carlton Reckling sold 5,000 shares of SIBN on 17 July. They now own 10,049 SIBN shares, or a 33% holding decrease.

Scott A Yerby sold 10,217 shares of SIBN on 18 July. They now own 9,767 SIBN shares, or a 51% holding decrease.

Anthony J Recupero sold 1,200 shares of SIBN on 1 August. They now own 18,854 SIBN shares, or a 6% holding decrease.